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Recombinant human activated protein C for the treatment of severe sepsis and septic shock: a study protocol for incorporating observational evidence using a Bayesian approach

INTRODUCTION: Activated protein C (aPC) plays a pivotal role in modulating a severe inflammatory response and is thought to be beneficial for patients with sepsis. However, several meta-analyses of randomised controlled trials (RCTs) show that aPC is not significantly associated with improved surviv...

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Detalles Bibliográficos
Autor principal:	Zhang, Zhongheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2014
Materias:	Intensive Care
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120342/ https://www.ncbi.nlm.nih.gov/pubmed/25082420 http://dx.doi.org/10.1136/bmjopen-2014-005622

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