Fructokinase activity mediates dehydration-induced renal injury

The epidemic of chronic kidney disease in Nicaragua (Mesoamerican nephropathy) has been linked with recurrent dehydration. Here we tested whether recurrent dehydration may cause renal injury by activation of the polyol pathway, resulting in the generation of endogenous fructose in the kidney that mi...

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Detalles Bibliográficos
Autores principales: Roncal Jimenez, Carlos A, Ishimoto, Takuji, Lanaspa, Miguel A, Rivard, Christopher J, Nakagawa, Takahiko, Ejaz, A. Ahsan, Cicerchi, Christina, Inaba, Shinichiro, Le, MyPhuong, Miyazaki, Makoto, Glaser, Jason, Correa-Rotter, Ricardo, González, Marvin A, Aragón, Aurora, Wesseling, Catharina, Sánchez-Lozada, Laura G, Johnson, Richard J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Basic Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120672/
https://www.ncbi.nlm.nih.gov/pubmed/24336030
http://dx.doi.org/10.1038/ki.2013.492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120672/
https://www.ncbi.nlm.nih.gov/pubmed/24336030
http://dx.doi.org/10.1038/ki.2013.492

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