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Brain disposition of α-Synuclein: roles of brain barrier systems and implications for Parkinson’s disease
Parkinson’s disease (PD) is a neurodegenerative disorder characterized by the accumulation of α-Synuclein (a-Syn) into Lewy body inclusions and the loss of dopaminergic neurons in the substantia nigra (SN). Accumulation of a-Syn can induce a progressive, cyclical pathology that results in the transm...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120720/ https://www.ncbi.nlm.nih.gov/pubmed/25093076 http://dx.doi.org/10.1186/2045-8118-11-17 |