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Brain disposition of α-Synuclein: roles of brain barrier systems and implications for Parkinson’s disease

Parkinson’s disease (PD) is a neurodegenerative disorder characterized by the accumulation of α-Synuclein (a-Syn) into Lewy body inclusions and the loss of dopaminergic neurons in the substantia nigra (SN). Accumulation of a-Syn can induce a progressive, cyclical pathology that results in the transm...

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Detalles Bibliográficos
Autores principales:	Bates, Christopher A, Zheng, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120720/ https://www.ncbi.nlm.nih.gov/pubmed/25093076 http://dx.doi.org/10.1186/2045-8118-11-17

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