Engineering processive DNA polymerases with maximum benefit at minimum cost

DNA polymerases need to be engineered to achieve optimal performance for biotechnological applications, which often require high fidelity replication when using modified nucleotides and when replicating difficult DNA sequences. These tasks are achieved for the bacteriophage T4 DNA polymerase by repl...

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Detalles Bibliográficos
Autores principales: Reha-Krantz, Linda J., Woodgate, Sandra, Goodman, Myron F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120765/
https://www.ncbi.nlm.nih.gov/pubmed/25136334
http://dx.doi.org/10.3389/fmicb.2014.00380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120765/
https://www.ncbi.nlm.nih.gov/pubmed/25136334
http://dx.doi.org/10.3389/fmicb.2014.00380

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