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Engineering processive DNA polymerases with maximum benefit at minimum cost
DNA polymerases need to be engineered to achieve optimal performance for biotechnological applications, which often require high fidelity replication when using modified nucleotides and when replicating difficult DNA sequences. These tasks are achieved for the bacteriophage T4 DNA polymerase by repl...
Autores principales: | Reha-Krantz, Linda J., Woodgate, Sandra, Goodman, Myron F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120765/ https://www.ncbi.nlm.nih.gov/pubmed/25136334 http://dx.doi.org/10.3389/fmicb.2014.00380 |
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