Tanshinone IIA Downregulates HMGB1 and TLR4 Expression in a Spinal Nerve Ligation Model of Neuropathic Pain

Fifty-four Sprague-Dawley rats weighing 200~240 g were randomly divided into sham-operated group (sham group), vehicle-treated SNL group (model group), and Tan IIA-treated SNL group (Tan IIA group). Tan IIA was administered intraperitoneally to rats in the Tan IIA-treated group at a dose of 30 mg/kg...

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Detalles Bibliográficos
Autores principales: Ma, Yu-Qing, Chen, Yi-Rong, Leng, Yu-Fang, Wu, Zhi-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120799/
https://www.ncbi.nlm.nih.gov/pubmed/25120576
http://dx.doi.org/10.1155/2014/639563

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120799/
https://www.ncbi.nlm.nih.gov/pubmed/25120576
http://dx.doi.org/10.1155/2014/639563

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