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Directing Human Induced Pluripotent Stem Cells into a Neurosensory Lineage for Auditory Neuron Replacement

Emerging therapies for sensorineural hearing loss include replacing damaged auditory neurons (ANs) using stem cells. Ultimately, it is important that these replacement cells can be patient-matched to avoid immunorejection. As human induced pluripotent stem cells (hiPSCs) can be obtained directly fro...

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Detalles Bibliográficos
Autores principales: Gunewardene, Niliksha, Bergen, Nicole Van, Crombie, Duncan, Needham, Karina, Dottori, Mirella, Nayagam, Bryony A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120935/
https://www.ncbi.nlm.nih.gov/pubmed/25126480
http://dx.doi.org/10.1089/biores.2014.0019