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Glycocalyx Remodeling with Proteoglycan Mimetics Promotes Neural Specification in Embryonic Stem Cells

[Image: see text] Growth factor (GF) signaling is a key determinant of stem cell fate. Interactions of GFs with their receptors are often mediated by heparan sulfate proteoglycans (HSPGs). Here, we report a cell surface engineering strategy that exploits the function of HSPGs to promote differentiat...

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Detalles Bibliográficos
Autores principales: Huang, Mia L., Smith, Raymond A. A., Trieger, Greg W., Godula, Kamil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121001/
https://www.ncbi.nlm.nih.gov/pubmed/25019314
http://dx.doi.org/10.1021/ja505012a