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C1GALT1 Promotes Invasive Phenotypes of Hepatocellular Carcinoma Cells by Modulating Integrin β1 Glycosylation and Activity

Cancer cell invasion and metastasis are the primary causes of treatment failure and death in hepatocellular carcinoma (HCC). We previously reported that core 1 β1,3-galactosyltransferase (C1GALT1) is frequently overexpressed in HCC tumors and its expression is associated with advanced tumor stage, m...

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Detalles Bibliográficos
Autores principales: Liu, Chiung-Hui, Hu, Rey-Heng, Huang, Miao-Juei, Lai, I-Rue, Chen, Chia-Hua, Lai, Hong-Shiee, Wu, Yao-Ming, Huang, Min-Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121071/
https://www.ncbi.nlm.nih.gov/pubmed/25089569
http://dx.doi.org/10.1371/journal.pone.0094995