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C1GALT1 Promotes Invasive Phenotypes of Hepatocellular Carcinoma Cells by Modulating Integrin β1 Glycosylation and Activity
Cancer cell invasion and metastasis are the primary causes of treatment failure and death in hepatocellular carcinoma (HCC). We previously reported that core 1 β1,3-galactosyltransferase (C1GALT1) is frequently overexpressed in HCC tumors and its expression is associated with advanced tumor stage, m...
Autores principales: | Liu, Chiung-Hui, Hu, Rey-Heng, Huang, Miao-Juei, Lai, I-Rue, Chen, Chia-Hua, Lai, Hong-Shiee, Wu, Yao-Ming, Huang, Min-Chuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121071/ https://www.ncbi.nlm.nih.gov/pubmed/25089569 http://dx.doi.org/10.1371/journal.pone.0094995 |
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