MicroRNA-30c reduces hyperlipidemia and atherosclerosis by decreasing lipid synthesis and lipoprotein secretion

Hyperlipidemia is a risk factor for various cardiovascular and metabolic disorders. Overproduction of lipoproteins, a process critically dependent on microsomal triglyceride transfer protein (MTP), can contribute to hyperlipidemia. We show that microRNA-30c (miR-30c) interacts with the 3′-untranslat...

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Detalles Bibliográficos
Autores principales: Soh, James, Iqbal, Jahangir, Queiroz, Joyce, Fernandez-Hernando, Carlos, Hussain, M. Mahmood
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121125/
https://www.ncbi.nlm.nih.gov/pubmed/23749231
http://dx.doi.org/10.1038/nm.3200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121125/
https://www.ncbi.nlm.nih.gov/pubmed/23749231
http://dx.doi.org/10.1038/nm.3200

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