Mutating RBF Can Enhance Its Pro-Apoptotic Activity and Uncovers a New Role in Tissue Homeostasis

The tumor suppressor retinoblastoma protein (pRb) is inactivated in a wide variety of cancers. While its role during cell cycle is well characterized, little is known about its properties on apoptosis regulation and apoptosis-induced cell responses. pRb shorter forms that can modulate pRB apoptotic...

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Detalles Bibliográficos
Autores principales: Milet, Cécile, Rincheval-Arnold, Aurore, Moriéras, Angéline, Clavier, Amandine, Garrigue, Alexandrine, Mignotte, Bernard, Guénal, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121136/
https://www.ncbi.nlm.nih.gov/pubmed/25089524
http://dx.doi.org/10.1371/journal.pone.0102902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121136/
https://www.ncbi.nlm.nih.gov/pubmed/25089524
http://dx.doi.org/10.1371/journal.pone.0102902

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