Engineering of Bispecific Affinity Proteins with High Affinity for ERBB2 and Adaptable Binding to Albumin

The epidermal growth factor receptor 2, ERBB2, is a well-validated target for cancer diagnostics and therapy. Recent studies suggest that the over-expression of this receptor in various cancers might also be exploited for antibody-based payload delivery, e.g. antibody drug conjugates. In such strate...

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Detalles Bibliográficos
Autores principales: Nilvebrant, Johan, Åstrand, Mikael, Georgieva-Kotseva, Maria, Björnmalm, Mattias, Löfblom, John, Hober, Sophia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121139/
https://www.ncbi.nlm.nih.gov/pubmed/25089830
http://dx.doi.org/10.1371/journal.pone.0103094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121139/
https://www.ncbi.nlm.nih.gov/pubmed/25089830
http://dx.doi.org/10.1371/journal.pone.0103094

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