Cholesterol Oxidase Binds TLR2 and Modulates Functional Responses of Human Macrophages

Cholesterol oxidase (ChoD) is considered to be an important virulence factor for Mycobacterium tuberculosis (Mtb), but its influence on macrophage activity is unknown. Here we used Nocardia erythropolis ChoD, which is very similar to the Mtb enzyme (70% identity at the amino-acid level), to evaluate...

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Detalles Bibliográficos
Autores principales: Bednarska, Katarzyna, Kielbik, Michal, Sulowska, Zofia, Dziadek, Jaroslaw, Klink, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121183/
https://www.ncbi.nlm.nih.gov/pubmed/25120288
http://dx.doi.org/10.1155/2014/498395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121183/
https://www.ncbi.nlm.nih.gov/pubmed/25120288
http://dx.doi.org/10.1155/2014/498395

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