Nucleolar Integrity Is Required for the Maintenance of Long-Term Synaptic Plasticity

Long-term memory (LTM) formation requires new protein synthesis and new gene expression. Based on our work in Aplysia, we hypothesized that the rRNA genes, stimulation-dependent targets of the enzyme Poly(ADP-ribose) polymerase-1 (PARP-1), are primary effectors of the activity-dependent changes in s...

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Detalles Bibliográficos
Autores principales: Allen, Kim D., Gourov, Andrei V., Harte, Christopher, Gao, Peng, Lee, Clarice, Sylvain, Darlene, Splett, Joshua M., Oxberry, William C., van de Nes, Paula S., Troy-Regier, Matthew J., Wolk, Jason, Alarcon, Juan M., Hernández, A. Iván
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121280/
https://www.ncbi.nlm.nih.gov/pubmed/25089620
http://dx.doi.org/10.1371/journal.pone.0104364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121280/
https://www.ncbi.nlm.nih.gov/pubmed/25089620
http://dx.doi.org/10.1371/journal.pone.0104364

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