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The role of p21-activated kinases in hepatocellular carcinoma metastasis
The p21-activated kinases (PAKs) are downstream effectors of the Rho family small GTPases as well as a wide variety of mitogenic factors and have been implicated in cancer formation, development and metastasis. PAKs phosphorylate a wide spectrum of substrates to mediate extracellular signals and reg...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121300/ https://www.ncbi.nlm.nih.gov/pubmed/25093037 http://dx.doi.org/10.1186/1750-2187-9-7 |