L-Carnitine Protects against Carboplatin-Mediated Renal Injury: AMPK- and PPARα-Dependent Inactivation of NFAT3

We have previously shown that carboplatin induces inflammation and apoptosis in renal tubular cells (RTCs) through the activation of the nuclear factor of activated T cells-3 (NFAT3) protein by reactive oxygen species (ROS), and that the ROS-mediated activation of NFAT3 is prevented by N-acetyl cyst...

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Detalles Bibliográficos
Autores principales: Sue, Yuh-Mou, Chou, Hsiu-Chu, Chang, Chih-Cheng, Yang, Nian-Jie, Chou, Ying, Juan, Shu-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121315/
https://www.ncbi.nlm.nih.gov/pubmed/25090113
http://dx.doi.org/10.1371/journal.pone.0104079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121315/
https://www.ncbi.nlm.nih.gov/pubmed/25090113
http://dx.doi.org/10.1371/journal.pone.0104079

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