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The RFTS Domain of Raf2 Is Required for Cul4 Interaction and Heterochromatin Integrity in Fission Yeast

Centromeric heterochromatin assembly in fission yeast is critical for faithful chromosome segregation at mitosis. Its assembly requires a concerted pathway of events whereby the RNA interference (RNAi) pathway guides H3K9 methylation to target sequences. H3K9 methylation, a hallmark of heterochromat...

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Detalles Bibliográficos
Autores principales: White, Sharon A., Buscaino, Alessia, Sanchez-Pulido, Luis, Ponting, Chris P., Nowicki, Matthew W., Allshire, Robin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121317/
https://www.ncbi.nlm.nih.gov/pubmed/25090107
http://dx.doi.org/10.1371/journal.pone.0104161