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Dendritic cells matured in the presence of TLR ligands overcome the immunosuppressive functions of regulatory T cells
Toll like receptor (TLR)-stimulated dendritic cells (DCs) are able to overcome the inhibitory activity of regulatory T cells (Tregs) and induce the proliferation of effector T cells. TLR-activated DCs secrete a soluble factor and act directly on Tregs to convert them into interferon γ-secreting T(H)...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Landes Bioscience
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121335/ https://www.ncbi.nlm.nih.gov/pubmed/25101219 http://dx.doi.org/10.4161/onci.27617 |