Targeting the adenosine A2b receptor in the tumor microenvironment overcomes local immunosuppression by myeloid-derived suppressor cells

Emerging evidence suggests that the adenosine A2b receptor (ADORA2B, also known as A2bR) plays a pivotal role in tumor progression. We have recently demonstrated that blocking A2bR stimulates T cell-mediated immunosurveillance in a melanoma model by impairing the influx of myeloid-deriver suppressor...

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Detalles Bibliográficos
Autores principales: Morello, Silvana, Miele, Lucio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121336/
https://www.ncbi.nlm.nih.gov/pubmed/25101221
http://dx.doi.org/10.4161/onci.27989

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121336/
https://www.ncbi.nlm.nih.gov/pubmed/25101221
http://dx.doi.org/10.4161/onci.27989

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