Cargando…

Constitutively active Notch1 signaling promotes endothelial-mesenchymal transition in a conditional transgenic mouse model

Endothelial-mesenchymal transition (EndoMT) is a process in which endothelial cells lose their cell-type-specific characteristics and gain a mesenchymal cell phenotype. The Notch signaling pathway is crucial in the regulation of EndoMT; however, its roles have not been fully studied in vivo. In a pr...

Descripción completa

Detalles Bibliográficos
Autores principales: LIU, JU, DONG, FENGYUN, JEONG, JAMES, MASUDA, TAKAHIRO, LOBE, CORRINNE G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121347/
https://www.ncbi.nlm.nih.gov/pubmed/24969754
http://dx.doi.org/10.3892/ijmm.2014.1818