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Constitutively active Notch1 signaling promotes endothelial-mesenchymal transition in a conditional transgenic mouse model
Endothelial-mesenchymal transition (EndoMT) is a process in which endothelial cells lose their cell-type-specific characteristics and gain a mesenchymal cell phenotype. The Notch signaling pathway is crucial in the regulation of EndoMT; however, its roles have not been fully studied in vivo. In a pr...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121347/ https://www.ncbi.nlm.nih.gov/pubmed/24969754 http://dx.doi.org/10.3892/ijmm.2014.1818 |