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Hydrodynamics-based transfection of rat interleukin-10 gene attenuates porcine serum-induced liver fibrosis in rats by inhibiting the activation of hepatic stellate cells

Liver fibrosis is the common pathological outcome for the majority of chronic liver diseases. Interleukin-10 (IL-10) is a cytokine that downregulates proinflammatory responses and has a modulatory effect on liver fibrogenesis. However, little is known regarding the effect of rat interleukin-10 (rIL-...

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Detalles Bibliográficos
Autores principales: HUANG, YUE-HONG, CHEN, YUN-XIN, ZHANG, LI-JUAN, CHEN, ZHI-XIN, WANG, XIAO-ZHONG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121348/
https://www.ncbi.nlm.nih.gov/pubmed/24993843
http://dx.doi.org/10.3892/ijmm.2014.1831