The transcriptional activity of Gli1 is negatively regulated by AMPK through Hedgehog partial agonism in hepatocellular carcinoma

The aberrant activation of the Hedgehog (Hh) signaling pathway has been implicated in a variety of malignancies, including hepatocellular carcinoma (HCC). The mammalian 5′ adenosine monophosphate-activated protein kinase (AMPK) plays a crucial role in cellular energy homeostasis. However, the intera...

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Detalles Bibliográficos
Autores principales: XU, QIURAN, LIU, XIN, ZHENG, XIN, YAO, YINGMIN, WANG, MAODE, LIU, QINGGUANG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121351/
https://www.ncbi.nlm.nih.gov/pubmed/25017332
http://dx.doi.org/10.3892/ijmm.2014.1847

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121351/
https://www.ncbi.nlm.nih.gov/pubmed/25017332
http://dx.doi.org/10.3892/ijmm.2014.1847

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