Epigenomic and transcriptomic signatures of a Klinefelter syndrome (47,XXY) karyotype in the brain

Klinefelter syndrome (KS) is the most common sex-chromosome aneuploidy in humans. Most affected individuals carry one extra X-chromosome (47,XXY karyotype) and the condition presents with a heterogeneous mix of reproductive, physical and psychiatric phenotypes. Although the mechanism(s) by which the...

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Detalles Bibliográficos
Autores principales: Viana, Joana, Pidsley, Ruth, Troakes, Claire, Spiers, Helen, Wong, Chloe CY, Al-Sarraj, Safa, Craig, Ian, Schalkwyk, Leonard, Mill, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121369/
https://www.ncbi.nlm.nih.gov/pubmed/24476718
http://dx.doi.org/10.4161/epi.27806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121369/
https://www.ncbi.nlm.nih.gov/pubmed/24476718
http://dx.doi.org/10.4161/epi.27806

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