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A reciprocal role of prostate cancer on stromal DNA damage

DNA damage found in prostate cancer-associated fibroblasts (CAF) promotes tumor progression. In the absence of somatic mutations in CAF, epigenetic changes dictate how stromal co-evolution is mediated in tumors. Seventy percent of prostate cancer patients lose expression of transforming growth facto...

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Detalles Bibliográficos
Autores principales: Banerjee, Jheelam, Mishra, Rajeev, Li, Xiaohong, Jackson, Roger S., Sharma, Adrija, Bhowmick, Neil A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121379/
https://www.ncbi.nlm.nih.gov/pubmed/24141771
http://dx.doi.org/10.1038/onc.2013.431