GPC3 expression in mouse ovarian cancer induces GPC3-specific T cell-mediated immune response through M1 macrophages and suppresses tumor growth

Glypican-3 (GPC3) is specifically expressed in ovarian clear cell carcinoma (OCCC), hepatocellular carcinoma (HCC), and melanoma and lung cancer. GPC3 is being explored as a potential candidate for OCCC and HCC immunotherapy. As a tumor-associated antigen, induction of immune response of GPC3 in ova...

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Detalles Bibliográficos
Autores principales: LUO, CHENHONG, SHIBATA, KIYOSUMI, SUZUKI, SHIRO, KAJIYAMA, HIROAKI, SENGA, TAKESHI, KOYA, YOSHIHIRO, DAIMON, MINA, YAMASHITA, MAMORU, KIKKAWA, FUMITAKA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121400/
https://www.ncbi.nlm.nih.gov/pubmed/24992906
http://dx.doi.org/10.3892/or.2014.3300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121400/
https://www.ncbi.nlm.nih.gov/pubmed/24992906
http://dx.doi.org/10.3892/or.2014.3300

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