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Towards combinatorial targeted therapy in melanoma: From pre-clinical evidence to clinical application (Review)

Over the last few years, clinical trials with BRAF and mitogen-activated protein/extracellular signal-regulated kinase (MEK) inhibitors have shown significant clinical activity in melanoma, but only a fraction of patients respond to these therapies, and development of resistance is frequent. This ha...

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Detalles Bibliográficos
Autores principales: GRAZIA, GIULIA, PENNA, ILARIA, PEROTTI, VALENTINA, ANICHINI, ANDREA, TASSI, ELENA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121406/
https://www.ncbi.nlm.nih.gov/pubmed/24920406
http://dx.doi.org/10.3892/ijo.2014.2491