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Towards combinatorial targeted therapy in melanoma: From pre-clinical evidence to clinical application (Review)
Over the last few years, clinical trials with BRAF and mitogen-activated protein/extracellular signal-regulated kinase (MEK) inhibitors have shown significant clinical activity in melanoma, but only a fraction of patients respond to these therapies, and development of resistance is frequent. This ha...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121406/ https://www.ncbi.nlm.nih.gov/pubmed/24920406 http://dx.doi.org/10.3892/ijo.2014.2491 |