Impact of 5-fluorouracil metabolizing enzymes on chemotherapy in patients with resectable colorectal cancer

Although 5-fluorouracil (5-FU) is an important drug for colorectal cancer (CRC) treatment, no useful biomarker is currently available to predict treatment response. Since 5-FU is converted into active or inactive forms by orotate phosphoribosyltransferase (OPRT) or dihydropyrimidine dehydrogenase (D...

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Detalles Bibliográficos
Autores principales: OCHIAI, TAKUMI, UMEKI, MASAHIKO, MIYAKE, HIROSHI, IIDA, TATSUMI, OKUMURA, MINORU, OHNO, KAZUHIDE, SAKAMOTO, MASASHI, MIYOSHI, NOBUKAZU, TAKAHASHI, MASAHIKO, TSUMURA, HIDENORI, TOKUNAGA, YUKIHIKO, NAITOU, HARUHIKO, FUKUI, TAKUJI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121408/
https://www.ncbi.nlm.nih.gov/pubmed/24994673
http://dx.doi.org/10.3892/or.2014.3299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121408/
https://www.ncbi.nlm.nih.gov/pubmed/24994673
http://dx.doi.org/10.3892/or.2014.3299

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