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Impact of 5-fluorouracil metabolizing enzymes on chemotherapy in patients with resectable colorectal cancer
Although 5-fluorouracil (5-FU) is an important drug for colorectal cancer (CRC) treatment, no useful biomarker is currently available to predict treatment response. Since 5-FU is converted into active or inactive forms by orotate phosphoribosyltransferase (OPRT) or dihydropyrimidine dehydrogenase (D...
Autores principales: | OCHIAI, TAKUMI, UMEKI, MASAHIKO, MIYAKE, HIROSHI, IIDA, TATSUMI, OKUMURA, MINORU, OHNO, KAZUHIDE, SAKAMOTO, MASASHI, MIYOSHI, NOBUKAZU, TAKAHASHI, MASAHIKO, TSUMURA, HIDENORI, TOKUNAGA, YUKIHIKO, NAITOU, HARUHIKO, FUKUI, TAKUJI |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121408/ https://www.ncbi.nlm.nih.gov/pubmed/24994673 http://dx.doi.org/10.3892/or.2014.3299 |
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