Inhibition of Cdk2 kinase activity selectively targets the CD44(+)/CD24(−/Low) stem-like subpopulation and restores chemosensitivity of SUM149PT triple-negative breast cancer cells

Inflammatory breast cancer (IBC) is an angioinvasive and most aggressive type of advanced breast cancer characterized by rapid proliferation, chemoresistance, early metastatic development and poor prognosis. IBC tumors display a triple-negative breast cancer (TNBC) phenotype characterized by centros...

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Detalles Bibliográficos
Autores principales: OPYRCHAL, MATEUSZ, SALISBURY, JEFFREY L., IANKOV, IANKO, GOETZ, MATHEW P., McCUBREY, JAMES, GAMBINO, MARIO W., MALATINO, LORENZO, PUCCIA, GIUSEPPE, INGLE, JAMES N., GALANIS, EVANTHIA, D’ASSORO, ANTONINO B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121417/
https://www.ncbi.nlm.nih.gov/pubmed/24970653
http://dx.doi.org/10.3892/ijo.2014.2523

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121417/
https://www.ncbi.nlm.nih.gov/pubmed/24970653
http://dx.doi.org/10.3892/ijo.2014.2523

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