Cargando…
Inhibition of Cdk2 kinase activity selectively targets the CD44(+)/CD24(−/Low) stem-like subpopulation and restores chemosensitivity of SUM149PT triple-negative breast cancer cells
Inflammatory breast cancer (IBC) is an angioinvasive and most aggressive type of advanced breast cancer characterized by rapid proliferation, chemoresistance, early metastatic development and poor prognosis. IBC tumors display a triple-negative breast cancer (TNBC) phenotype characterized by centros...
Autores principales: | OPYRCHAL, MATEUSZ, SALISBURY, JEFFREY L., IANKOV, IANKO, GOETZ, MATHEW P., McCUBREY, JAMES, GAMBINO, MARIO W., MALATINO, LORENZO, PUCCIA, GIUSEPPE, INGLE, JAMES N., GALANIS, EVANTHIA, D’ASSORO, ANTONINO B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121417/ https://www.ncbi.nlm.nih.gov/pubmed/24970653 http://dx.doi.org/10.3892/ijo.2014.2523 |
Ejemplares similares
-
Molecular targeting of the Aurora-A/SMAD5 oncogenic axis restores chemosensitivity in human breast cancer cells
por: Opyrchal, Mateusz, et al.
Publicado: (2017) -
Inhibition of Cdk2 activity decreases Aurora-A kinase centrosomal localization and prevents centrosome amplification in breast cancer cells
por: LEONTOVICH, ALEXEY A., et al.
Publicado: (2013) -
Aurora-A Mitotic Kinase Induces Endocrine Resistance through Down-Regulation of ERα Expression in Initially ERα+ Breast Cancer Cells
por: Opyrchal, Mateusz, et al.
Publicado: (2014) -
Inhibition of the Aurora A kinase augments the anti-tumor efficacy of oncolytic measles virotherapy
por: Iankov, Ianko D., et al.
Publicado: (2015) -
Aurora-A overexpression is linked to development of aggressive teratomas derived from human iPS cells
por: Ohmine, Seiga, et al.
Publicado: (2018)