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Transforming growth factor-β1 reduces apoptosis via autophagy activation in hepatic stellate cells

Autophagy is a metabolic process that is important in fibrogenesis, in which cellular components are degraded by lysosomal machinery. Transforming growth factor β1 (TGF-β1) is a potent fibrogenic cytokine involved in liver fibrosis; however, it remains elusive whether autophagy is regulated by TGF-β...

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Detalles Bibliográficos
Autores principales: FU, MEI-YA, HE, YA-JUN, LV, XIA, LIU, ZHI-HE, SHEN, YAN, YE, GUO-RONG, DENG, YAN-MEI, SHU, JIAN-CHANG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121427/
https://www.ncbi.nlm.nih.gov/pubmed/25059289
http://dx.doi.org/10.3892/mmr.2014.2383