Self-replicating Replicon-RNA Delivery to Dendritic Cells by Chitosan-nanoparticles for Translation In Vitro and In Vivo

Self-amplifying replicon RNA (RepRNA) possesses high potential for increasing antigen load within dendritic cells (DCs). The major aim of the present work was to define how RepRNA delivered by biodegradable, chitosan-based nanoparticulate delivery vehicles (nanogel-alginate (NGA)) interacts with DCs...

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Detalles Bibliográficos
Autores principales: McCullough, Kenneth C, Bassi, Isabelle, Milona, Panagiota, Suter, Rolf, Thomann-Harwood, Lisa, Englezou, Pavlos, Démoulins, Thomas, Ruggli, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121514/
https://www.ncbi.nlm.nih.gov/pubmed/25004099
http://dx.doi.org/10.1038/mtna.2014.24

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121514/
https://www.ncbi.nlm.nih.gov/pubmed/25004099
http://dx.doi.org/10.1038/mtna.2014.24

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