ATR Mediates a Checkpoint at the Nuclear Envelope in Response to Mechanical Stress

ATR controls chromosome integrity and chromatin dynamics. We have previously shown that yeast Mec1/ATR promotes chromatin detachment from the nuclear envelope to counteract aberrant topological transitions during DNA replication. Here, we provide evidence that ATR activity at the nuclear envelope re...

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Detalles Bibliográficos
Autores principales: Kumar, Amit, Mazzanti, Michele, Mistrik, Martin, Kosar, Martin, Beznoussenko, Galina V., Mironov, Alexandre A., Garrè, Massimiliano, Parazzoli, Dario, Shivashankar, G.V., Scita, Giorgio, Bartek, Jiri, Foiani, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121522/
https://www.ncbi.nlm.nih.gov/pubmed/25083873
http://dx.doi.org/10.1016/j.cell.2014.05.046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121522/
https://www.ncbi.nlm.nih.gov/pubmed/25083873
http://dx.doi.org/10.1016/j.cell.2014.05.046

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