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ER Stress-Induced Clearance of Misfolded GPI-Anchored Proteins via the Secretory Pathway
Proteins destined for the cell surface are first assessed in the endoplasmic reticulum (ER) for proper folding before release into the secretory pathway. This ensures that defective proteins are normally prevented from entering the extracellular environment, where they could be disruptive. Here, we...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121523/ https://www.ncbi.nlm.nih.gov/pubmed/25083867 http://dx.doi.org/10.1016/j.cell.2014.06.026 |