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ER Stress-Induced Clearance of Misfolded GPI-Anchored Proteins via the Secretory Pathway

Proteins destined for the cell surface are first assessed in the endoplasmic reticulum (ER) for proper folding before release into the secretory pathway. This ensures that defective proteins are normally prevented from entering the extracellular environment, where they could be disruptive. Here, we...

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Detalles Bibliográficos
Autores principales: Satpute-Krishnan, Prasanna, Ajinkya, Monica, Bhat, Savithri, Itakura, Eisuke, Hegde, Ramanujan S., Lippincott-Schwartz, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121523/
https://www.ncbi.nlm.nih.gov/pubmed/25083867
http://dx.doi.org/10.1016/j.cell.2014.06.026