Cargando…
ER Stress-Induced Clearance of Misfolded GPI-Anchored Proteins via the Secretory Pathway
Proteins destined for the cell surface are first assessed in the endoplasmic reticulum (ER) for proper folding before release into the secretory pathway. This ensures that defective proteins are normally prevented from entering the extracellular environment, where they could be disruptive. Here, we...
Autores principales: | Satpute-Krishnan, Prasanna, Ajinkya, Monica, Bhat, Savithri, Itakura, Eisuke, Hegde, Ramanujan S., Lippincott-Schwartz, Jennifer |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121523/ https://www.ncbi.nlm.nih.gov/pubmed/25083867 http://dx.doi.org/10.1016/j.cell.2014.06.026 |
Ejemplares similares
-
Misfolded GPI-anchored proteins are escorted through the secretory pathway by ER-derived factors
por: Zavodszky, Eszter, et al.
Publicado: (2019) -
Competition for calnexin binding regulates secretion and turnover of misfolded GPI-anchored proteins
por: Cheatham, Amber M., et al.
Publicado: (2023) -
The ER v-SNAREs are required for GPI-anchored protein sorting from other secretory proteins upon exit from the ER
por: Morsomme, Pierre, et al.
Publicado: (2003) -
Endoplasmic reticulum–associated degradation and disposal of misfolded GPI-anchored proteins in Trypanosoma brucei
por: Tiengwe, Calvin, et al.
Publicado: (2018) -
Limited ER quality control for GPI-anchored proteins
por: Sikorska, Natalia, et al.
Publicado: (2016)