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Novel Humanized Recombinant T Cell Receptor Ligands Protect the Female Brain After Experimental Stroke

Transmigration of peripheral leukocytes to the brain is a major contributor to cerebral ischemic cell death mechanisms. Humanized partial major histocompatibility complex class II constructs (pMHC), covalently linked to myelin peptides, are effective for treating experimental stroke in males, but ne...

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Detalles Bibliográficos
Autores principales: Pan, Jie, Palmateer, Julie, Schallert, Timothy, Hart, Madison, Pandya, Arushi, Vandenbark, Arthur A., Offner, Halina, Hurn, Patricia D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121525/
https://www.ncbi.nlm.nih.gov/pubmed/24838614
http://dx.doi.org/10.1007/s12975-014-0345-y