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Spatial sequestration of misfolded proteins by a dynamic chaperone pathway enhances cellular fitness to stress
The extensive links between proteotoxic stress, protein aggregation and pathologies ranging from aging to neurodegeneration underscore the importance of understanding how cells manage protein misfolding. Using live-cell imaging, we here determine the fate of stress-induced misfolded proteins from th...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121856/ https://www.ncbi.nlm.nih.gov/pubmed/24036477 http://dx.doi.org/10.1038/ncb2838 |