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Dynamic myosin phosphorylation regulates contractile pulses and tissue integrity during epithelial morphogenesis
Apical constriction is a cell shape change that promotes epithelial bending. Activation of nonmuscle myosin II (Myo-II) by kinases such as Rho-associated kinase (Rok) is important to generate contractile force during apical constriction. Cycles of Myo-II assembly and disassembly, or pulses, are asso...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121972/ https://www.ncbi.nlm.nih.gov/pubmed/25092658 http://dx.doi.org/10.1083/jcb.201402004 |