Slit2N and Robo4 regulate lymphangiogenesis through the VEGF-C/VEGFR-3 pathway

BACKGROUND: Signaling through vascular endothelial growth factor C (VEGF–C) and VEGF receptor 3 (VEGFR-3) plays a central role in lymphangiogenesis and the metastasis of several cancers via the lymphatics. Recently, the Slit2/Robo4 pathway has been recognized as a modulator of vascular permeability...

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Detalles Bibliográficos
Autores principales: Yu, Jinlong, Zhang, Xuefeng, Kuzontkoski, Paula M, Jiang, Shuxian, Zhu, Weiquan, Li, Dean Y, Groopman, Jerome E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122147/
https://www.ncbi.nlm.nih.gov/pubmed/24708522
http://dx.doi.org/10.1186/1478-811X-12-25

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122147/
https://www.ncbi.nlm.nih.gov/pubmed/24708522
http://dx.doi.org/10.1186/1478-811X-12-25

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