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Novel artificial cell microencapsulation of a complex gliclazide-deoxycholic bile acid formulation: a characterization study

Gliclazide (G) is an antidiabetic drug commonly used in type 2 diabetes. It has extrapancreatic hypoglycemic effects, which makes it a good candidate in type 1 diabetes (T1D). In previous studies, we have shown that a gliclazide-bile acid mixture exerted a hypoglycemic effect in a rat model of T1D....

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Detalles Bibliográficos
Autores principales: Mooranian, Armin, Negrulj, Rebecca, Chen-Tan, Nigel, Al-Sallami, Hesham S, Fang, Zhongxiang, Mukkur, Trilochan, Mikov, Momir, Golocorbin-Kon, Svetlana, Fakhoury, Marc, Arfuso, Frank, Al-Salami, Hani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122185/
https://www.ncbi.nlm.nih.gov/pubmed/25114507
http://dx.doi.org/10.2147/DDDT.S65396