Heterodimerization of p45–p75 Modulates p75 Signaling: Structural Basis and Mechanism of Action

The p75 neurotrophin receptor, a member of the tumor necrosis factor receptor superfamily, is required as a co-receptor for the Nogo receptor (NgR) to mediate the activity of myelin-associated inhibitors such as Nogo, MAG, and OMgp. p45/NRH2/PLAIDD is a p75 homologue and contains a death domain (DD)...

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Detalles Bibliográficos
Autores principales: Vilar, Marçal, Sung, Tsung-Chang, Chen, Zhijiang, García-Carpio, Irmina, Fernandez, Eva M., Xu, Jiqing, Riek, Roland, Lee, Kuo-Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122344/
https://www.ncbi.nlm.nih.gov/pubmed/25093680
http://dx.doi.org/10.1371/journal.pbio.1001918

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122344/
https://www.ncbi.nlm.nih.gov/pubmed/25093680
http://dx.doi.org/10.1371/journal.pbio.1001918

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