Dysregulated Cytokine Production by Dendritic Cells Modulates B Cell Responses in the NZM2410 Mouse Model of Lupus

The breakdown in tolerance of autoreactive B cells in the lupus-prone NZM2410-derived B6.Sle1.Sle2.Sle3 (TC) mice results in the secretion of autoantibodies. TC dendritic cells (DCs) enhance B cell proliferation and antibody secretion in a cytokine-dependent manner. However, the specific cytokine mi...

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Detalles Bibliográficos
Autores principales: Sang, Allison, Zheng, Ying-Yi, Yin, Yiming, Dozmorov, Igor, Li, Hao, Hsu, Hui-Chen, Mountz, John D., Morel, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122346/
https://www.ncbi.nlm.nih.gov/pubmed/25093822
http://dx.doi.org/10.1371/journal.pone.0102151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122346/
https://www.ncbi.nlm.nih.gov/pubmed/25093822
http://dx.doi.org/10.1371/journal.pone.0102151

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