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Early Skewed Distribution of Total and HIV-Specific CD8(+) T-Cell Memory Phenotypes during Primary HIV Infection Is Related to Reduced Antiviral Activity and Faster Disease Progression
The important role of the CD8(+) T-cells on HIV control is well established. However, correlates of immune protection remain elusive. Although the importance of CD8(+) T-cell specificity and functionality in virus control has been underscored, further unraveling the link between CD8(+) T-cell differ...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122399/ https://www.ncbi.nlm.nih.gov/pubmed/25093660 http://dx.doi.org/10.1371/journal.pone.0104235 |