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Methylation Profiles Reveal Distinct Subgroup of Hepatocellular Carcinoma Patients with Poor Prognosis

Hepatocellular Carcinoma (HCC) is one of the leading causes of cancer-associated mortality worldwide. However, the role of epigenetic changes such as aberrant DNA methylation in hepatocarcinogenesis remains largely unclear. In this study, we examined the methylation profiles of 59 HCC patients. Usin...

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Detalles Bibliográficos
Autores principales: Mah, Way-Champ, Thurnherr, Thomas, Chow, Pierce K. H., Chung, Alexander Y. F., Ooi, London L. P. J., Toh, Han Chong, Teh, Bin Tean, Saunthararajah, Yogen, Lee, Caroline G. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122406/
https://www.ncbi.nlm.nih.gov/pubmed/25093504
http://dx.doi.org/10.1371/journal.pone.0104158