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Partial Deletion of eNOS Gene Causes Hyperinsulinemic State, Unbalance of Cardiac Insulin Signaling Pathways and Coronary Dysfunction Independently of High Fat Diet

Abnormalities in eNOS gene, possibly interacting with high fat diet (HFD), affect peripheral vascular function and glucose metabolism. The relative role of eNOS gene, HFD and metabolic derangement on coronary function has not been fully elucidated. We test whether eNOS gene deficiency per se or in a...

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Detalles Bibliográficos
Autores principales: Vecoli, Cecilia, Novelli, Michela, Pippa, Anna, Giacopelli, Daniela, Beffy, Pascale, Masiello, Pellegrino, L’Abbate, Antonio, Neglia, Danilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122412/
https://www.ncbi.nlm.nih.gov/pubmed/25093405
http://dx.doi.org/10.1371/journal.pone.0104156