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Partial Deletion of eNOS Gene Causes Hyperinsulinemic State, Unbalance of Cardiac Insulin Signaling Pathways and Coronary Dysfunction Independently of High Fat Diet
Abnormalities in eNOS gene, possibly interacting with high fat diet (HFD), affect peripheral vascular function and glucose metabolism. The relative role of eNOS gene, HFD and metabolic derangement on coronary function has not been fully elucidated. We test whether eNOS gene deficiency per se or in a...
Autores principales: | Vecoli, Cecilia, Novelli, Michela, Pippa, Anna, Giacopelli, Daniela, Beffy, Pascale, Masiello, Pellegrino, L’Abbate, Antonio, Neglia, Danilo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122412/ https://www.ncbi.nlm.nih.gov/pubmed/25093405 http://dx.doi.org/10.1371/journal.pone.0104156 |
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