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Cyclin-Dependent Kinase 5 Is Involved in the Phosphorylation of Gephyrin and Clustering of GABA(A) Receptors at Inhibitory Synapses of Hippocampal Neurons

CDK5 has been implicated in neural functions including growth, neuronal migration, synaptic transmission and plasticity of excitatory chemical synapses. Here we report robust effects of CDK5 on phosphorylation of the postsynaptic scaffold protein gephyrin and clustering of inhibitory GABA(A) recepto...

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Detalles Bibliográficos
Autores principales: Kalbouneh, Heba, Schlicksupp, Andrea, Kirsch, Joachim, Kuhse, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122414/
https://www.ncbi.nlm.nih.gov/pubmed/25093719
http://dx.doi.org/10.1371/journal.pone.0104256